HIV and TB

• related: HIV, ID, immune reconstitution inflammatory syndrome

• IRIS common in TB patients with HIV
• interferon gamma poor indicator of active TB
• might not mount response to have positive interferon gamma
• treat with rifabutin over rifampin

The timing of his presentation is consistent with the immune reconstitution inflammatory syndrome (IRIS) (median 48 days), the return

cryptococcus

• related: ID, HIV, immune reconstitution inflammatory syndrome

• cryptococcus
• Starting HAART can cause IRIS
• Wait 5 weeks before starting HAART

Types:

• neoformans most common
• agathi: more tropical. Has decreased activity to fluconazole
• usually inhaled

Demographics

• BMT: less b/c ppx fluconazole
• alemduzumab: CD 52
• corticosteroids use
• calcin